Isolation, Characterization and Evaluation of Anti-convulsant Activity of Rubus Antidiabetic Activity of the Plant Abutilon indicum in Streptozotocin Induced. Abutilon hirtum extract and fractions exhibited anti-inflammatory analgesic, antipyretic and antipyretic activities which may be attributed by the. Abutilon indicum Sweet is an Asia phytomedicine traditionally used to treat several disorders, including diabetes mellitus. However, molecular.

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View at Google Scholar N. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and abuilon in any medium, provided the original work is properly cited.

The STZ-induced diabetic rats were randomly allocated into four groups 6—9 rats per group A. The findings of antidiabetic properties in this study are summarized in Figure 7and support the ethnobotanical use of A.

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We found that A. Table of Contents Alerts.

The presence of narrow rectangular and thick walled epidermimal cells, trichomes and vascular bundles connected to the abaxial epidermis in the lamina, rosette cells, raphide, petioles without wings etc. As shown in Figure 6the cells treated with the extract increased relative luciferase unit Antidiabetci in a dose-response manner. Standardization problems arise from the complex composition of drugs which are used in the form of whole plant, parts of the plants and of plant extract.

The oil is also an ingradient in many ointments, liniments and lotions for treating minor aches and pains as well as colds, when actviity externally. As there is no detailed on the standardisation work reported on stem, the physicochemical parameters, brief study on pharmacological activities and microbial contamination analysis are carried out. Mukhtar, Sayeed Ahmad Abstract. Thus, these results provide evidence that these compounds may lead to affect the antidiabetic activity of A.


In this report, we examined whether the extract of A. The results demonstrated that administration of A. Rajesh Garg and V.

However, molecular mechanisms supporting the antidiabetic effect of A. Sweet is an Asian phytomedicine traditionally used to treat several disorders, including diabetes mellitus.

The luciferase activity was expressed as a ratio of firefly to renilla luciferase activity. Similarly petroleum ether extract and benzene extract were found to possess very good analgesic property.

Traditionally the plant parts are used as sour, astringent and diuretic and is useful in conditions such vata, tumours, fever, neuralgia and splenopathy. The species suggests phytomedicine for anti-inflammatory, antimicrobial, antibacterial activities with industrial applications which are based on the antioxidant potential of the species.

Since troglitazone TGZ was voluntarily withdrawn from the market in March due to occurrence of severe idiosyncratic liver injury, it is necessary to establish a safer compound that shows antidiabetic activity. The results revealed that the use of leaves in controlling diabetes mellitus is justifiable. The medicinal plants are widely used by the traditional medical practitioners for curing various diseases in their day to day practice. Crude extract of A.

Anti-diabetic and analgesic activity of leaves of abutilon indicum

In addition all the extracts have shown CNS depressant activity. With respect to its traditional use, A. The alkaloid berberine has also been reported to activate GLUT1-mediated glucose uptake [ 48 ]. The animals were fed with free access to a commercial pellet diet C.

The aim of this study was to evaluate whether extract of Activitg. Clayton, Medical Plants in Thailandvol. View at Google Scholar M.

Assays were performed in triplicate for each experiment group as previously described [ 24 ]. Binding Activity of A.

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Its Bioactivities and Evaluation abutilpn Physicochemical Properties. In the follow-up studies, we examined potential mechanisms underlying the improvement in glucose utilization by the extract. Results from other researchers have shown that this plant also contains saponins and glycosides [ 10 ]. Extracts of the roxburgii were tested for growth inhibitory against bacterial plant pathogens, mosquito.


Volume2,Issue2 – Pharmacognosy Phytochemistry

Abstract Abutilon indicum L. Analgesic principles from this plant were also isolated [ 17 ], and its polyherbal formulations have been reported as being effective in treating diabetes and hyperlipidemia, and effective as free radical scavengers [ 18 — 20 ].

In fact, it has been known that the extrapancreatic action of glibenclamide has an important role to inhibit glucose production by liver and improve carbohydrate metabolism in diabetes [ 3435 ], and increases glucose disposal by actuvity GLUT1 protein at the plasma membrane of muscle [ 36 ].

By clicking on Request Paper you Agree to pay the above mentioned cost per paper. Adiponectin is exclusively expressed by mature adipocytes and is the most abundant circulating adipokine.

The plant of Abutilon indicum is available in reach source at Melghat tiger reserve forest area. As shown in Figure 1administration of A. Journal Issues Vol 20, Dec.

Most plants with antidiabetic properties have been found to contain metabolites such as glycosides, alkaloids and flavonoids [ 9 ].

Specific oligonucleotide primers were designed using the Primer3 program http: Sweet is an erect, branched shrub of 0. Then, the crude extracts or insulin used as the positive control xctivity added as follows: The distribution region plays an important determinant of pine distribution and abundance in the landscape.